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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES10118.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES10118.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
This gene encodes a small GTPase of the Ras superfamily. Rab proteins are involved in the... more
Product information "Anti-RAB23"
This gene encodes a small GTPase of the Ras superfamily. Rab proteins are involved in the regulation of diverse cellular functions associated with intracellular membrane trafficking, including autophagy and immune response to bacterial infection. The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling. Disruption of this gene has been implicated in Carpenter syndrome as well as cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013], Protein function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Together with SUFU, prevents nuclear import of GLI1, and thereby inhibits GLI1 transcription factor activity. Regulates GLI1 in differentiating chondrocytes. Likewise, regulates GLI3 proteolytic processing and modulates GLI2 and GLI3 transcription factor activity. Plays a role in autophagic vacuole assembly, and mediates defense against pathogens, such as S.aureus, by promoting their capture by autophagosomes that then merge with lysosomes. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000. Cellular localization: Cell membrane , Lipid-anchor , Cytoplasmic side . Cytoplasm . Cytoplasmic vesicle, autophagosome . Endosome membrane . Cytoplasmic vesicle, phagosome . Cytoplasmic vesicle, phagosome membrane , Lipid-anchor , Cytoplasmic side . Recruited to phagosomes containing S.aureus or M.tuberculosis. .
Keywords: | Anti-RAB23, Anti-HSPC137, Anti-Ras-related protein Rab-23, RAB23 rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES10118 |
Properties
Application: | WB, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, rat, mouse, |
Immunogen: | Synthesized peptide derived from human protein . at AA range: 120-200 |
MW: | 26 kD |
Format: | Purified |
Database Information
KEGG ID : | K06234 | Matching products |
UniProt ID : | Q9ULC3 | Matching products |
Gene ID | GeneID 51715 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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