Anti-PSP1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A303-205A-T	10 µl (2 µg)		-		2 - 8 business days*		164.00€
A303-205A	100 µl		-		2 - 8 business days*		588.00€

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Protein function: Regulates, cooperatively with NONO and SFPQ, androgen receptor-mediated gene... more

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Product information "Anti-PSP1"

Protein function: Regulates, cooperatively with NONO and SFPQ, androgen receptor-mediated gene transcription activity in Sertoli cell line. Binds to poly(A), poly(G) and poly(U) RNA homopolymers. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Together with NONO, required for the formation of nuclear paraspeckles. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway. [The UniProt Consortium]

Keywords:	Anti-PSP1, Anti-PSPC1, Anti-Paraspeckle protein 1, Anti-Paraspeckle component 1
Supplier:	Bethyl Laboratories
Supplier-Nr:	A303-205A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: rat, bovine)
Immunogen:	synthetic peptide. The epitope recognized by A303-205A-T maps to a region between residue 1 and 50 of human Paraspeckle Protein 1 using the numbering given in entry NP_001035879.1 (GeneID 55269).
Format:	Antigen Affinity Purified