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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ARG43996.50 | 50 µg | - | - |
6 - 14 business days* |
520.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Component of the 26S proteasome, a multiprotein complex involved in the... more
Product information "Anti-PSMD14"
Protein function: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. The PSMD14 subunit is a metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains within the complex. Plays a role in response to double-strand breaks (DSBs): acts as a regulator of non-homologous end joining (NHEJ) by cleaving 'Lys-63'-linked polyubiquitin, thereby promoting retention of JMJD2A/KDM4A on chromatin and restricting TP53BP1 accumulation. Also involved in homologous recombination repair by promoting RAD51 loading. [The UniProt Consortium]
Keywords: | Anti-POH1, Anti-PSMD14, Anti-26S proteasome regulatory subunit RPN11, Anti-26S proteasome regulatory subunit RPN11, Anti-26S proteasome-associated PAD1 homolog 1, Anti-26S proteasome-associated PAD1 homolog 1, Anti-26S proteasome non-ATPase regulatory sub |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG43996 |
Properties
Application: | ELISA, FC, ICC, IF, IHC (paraffin), WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Human PSMD14 recombinant protein |
MW: | 35 kD |
Database Information
KEGG ID : | K03030 | Matching products |
UniProt ID : | O00487 | Matching products |
Gene ID | GeneID 10213 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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