Anti-Proteinase 3/PR3

Anti-Proteinase 3/PR3
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-91805.60 60 µl -

7 - 16 business days*

198.00€
E-AB-91805.120 120 µl -

7 - 16 business days*

317.00€
E-AB-91805.200 200 µl -

7 - 16 business days*

525.00€
 
Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I,... more
Product information "Anti-Proteinase 3/PR3"
Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro. By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration. May play a role in neutrophil transendothelial migration, probably when associated with CD177. Protein function: Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:3198760, PubMed:2033050, PubMed:28240246). By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369). May play a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed:22266279). [The UniProt Consortium]
Keywords: MBN, P29, PR3, NP-4, PR-3, AGP7, PRTN3, Myeloblastin, C-ANCA antigen, Wegener autoantigen, Leukocyte proteinase 3, Neutrophil proteinase 4, Proteinase 3/PR3 Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-91805

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: rat
Immunogen: Recombinant fusion protein of human Proteinase 3/PR3

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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