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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V4177-20UG | 20 µg | - | - |
3 - 10 business days* |
332.00€
|
||
NSJ-V4177-100UG | 100 µg | - | - |
3 - 10 business days* |
752.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Progesterone is one of... more
Product information "Anti-Progesterone Receptor, clone PGR/8099R"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Progesterone is one of the central regulators of female reproduction. In breast development, progesterone is involved in the formation of lobular-alveolar structures and also affects differentiation in the breast by modulation of milk protein synthesis. The cellular effects of progesterone are mediated through progesterone receptors (PR). PR, a protein with 946 amino acids, is a ligand-activated transcription factor member of the steroid receptor super family of nuclear receptors. PR is predominantly expressed in female sex steroid responsive tissues such as the mammary gland, uterus and ovary but is also found in other tissues such as endocrine cells of the Langerhans' islets. The estrogen receptor (ER) and PR status has been used for over 20 years as a predictor of breast carcinoma responsiveness to endocrine therapy and as a prognostic indicator for early recurrence. Protein function: The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Depending on the isoform, progesterone receptor functions as a transcriptional activator or repressor. [The UniProt Consortium]
Keywords: | Anti-PR, Anti-PGR, Anti-NR3C3, Anti-Progesterone receptor, Anti-Nuclear receptor subfamily 3 group C member 3, Progesterone Receptor Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V4177 |
Properties
Application: | IHC (paraffin) |
Antibody Type: | Monoclonal |
Clone: | PGR/8099R |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | A recombinant partial protein (within amino acids 1-200) from the human protein |
Format: | Purified |
Database Information
KEGG ID : | K08556 | Matching products |
UniProt ID : | P06401 | Matching products |
Gene ID | GeneID 5241 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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