280 products were found matching "K08556"!

The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Human progesterone receptor (PR) is expressed as two forms: the full length PR-B and the short form PR-A. PR-A lacks the first 164 amino acid...

Antibody in 1X PBS with 0.05% BSA, 0.05% sodium azide. Progesterone receptor (PGR) is a ligand-activated nuclear hormone receptor that regulates transcriptional responses to progesterone signaling in hormone-responsive tissues. Progesterone Receptor Antibody for IHC targets this steroid hormone receptor, also known...

Description: Onapristone, a progesterone receptor antagonist, is used potentially for the treatment of breast cancer, advanced prostate cancer, and inducer of vaginal bleeding. Target: Others. Smiles: C[C@]12[C@]([C@]3(C([C@H](C1)C4=CC=C(N(C)C)C=C4)=C5C(CC3)=CC(=O)CC5)[H])(CC[C@@]2(CCCO)O)[H]. References: Rezai K,...

Description: Norethindrone acetate (19-Norethindroneacetate) is an oestrogen with inhibitory effects on adolescent menstruation and hepatic adenomas and is often used in combination with progestins in the study of endometriosis. Target: Progesterone Receptor, Estrogen Receptor/ERR. Smiles:...

A progesterone receptor antagonist. It is an effective late post-coital contraceptive. Active against ovarian cancer, and induces apoptosis through modulation of HPV E6/E7 in dexamethasone treated cervical cacinoma cells.

The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Depending on the isoform, progesterone receptor functions as transcriptional activator or repressor.

Mifepristone is an antagonist of glucocorticoid, progesterone, and androgen receptors (Kis = 0.1, 0.64, and 0.65 nM, respectively). It is selective for these receptors over the mineralocorticoid receptor (MR), estrogen receptor alpha (ERalpha), and ERbeta (Kis = 640, >200, and >750 nM, respectively). In cell-based...

Progesterone, along with pregnenolone, is the biosynthetic precursor of all other steroid hormones. Progesterone is synthesized from cholesterol by the sequential action of desmolase in the mitochondria, which produces pregnenolone, followed by Delta4,5-isomerase in the outer mitochondrial membrane and smooth...

Progesterone-d9 is intended for use as an internal standard for the quantification of progesterone (Cay-15876) by GC- or LC-MS. Progesterone is the biosynthetic precursor of all other steroid hormones. Progesterone is synthesized from cholesterol by the sequential action of desmolase in the mitochondria, which...

Danazol is a derivative of testosterone (Cay-15645) and ethisterone that can bind to androgen receptors and sex hormone-binding globulin causing a 3-fold increase in free testosterone. It possesses weak androgenic effects and inhibits the production of gonadotropins. It has been used to address symptoms of...

Medroxyprogesterone 17-acetate is a synthetic progestogen.,, It prevents fertilization and increases the rate of transport of eggs from the fallopian tubes to the uterus in female ferrets when administered prior to ovulation. Medroxyprogesterone 17-acetate reversibly blocks ovulation in rats when injected on the...

Norethynodrel is a synthetic progestin. In vivo, norethynodrel (10 mg/animal per day) reduces fetal implantation and induces fetal resorption in mated female rats. Formulations containing norethynodrel have been used as oral contraceptives.Formal Name: 17alpha-hydroxy-19-norpregn-5(10)-en-20-yn-3-one. CAS Number:...