Anti-PRG3 (p53 Responsive Gene 3, Apoptosis Inducing Factor (AIF) Homologous Mitochondrion Associate

Anti-PRG3 (p53 Responsive Gene 3, Apoptosis Inducing Factor (AIF) Homologous Mitochondrion Associate
Item number Size Datasheet Manual SDS Delivery time Quantity Price
P8930-02.100 100 µl - -

3 - 19 business days

498.00€
 
The p53 tumor suppressor protein induces cell cycle arrest or apoptosis in response to cellular... more
Product information "Anti-PRG3 (p53 Responsive Gene 3, Apoptosis Inducing Factor (AIF) Homologous Mitochondrion Associate"
The p53 tumor suppressor protein induces cell cycle arrest or apoptosis in response to cellular stresses. PRG3 (p53-responsive gene 3), is induced specifically under p53-dependent apoptotic conditions in human colon cancer cells. PRG3 has significant homology to bacterial oxidoreductases and the apoptosis-inducing factor, AIF. Unlike AIF, PRG3 localizes in the cytoplasm and its ectopic expression induces apoptosis. The PRG3 gene is thus a novel p53 target gene in a p53-dependent apoptosis pathway. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Supplier: United States Biological
Supplier-Nr: P8930-02

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: A synthetic peptide made to residues 170-185 [VTLIHSQVALADKELL] of the 41kD human PRG3 protein. This sequence is 87% identical in mouse.
Purity: Purified by immunoaffinity chromatography.
Format: Affinity Purified

Database Information

Handling & Safety

Storage: -20°C (-20°C Glycerol)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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