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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein... more
Product information "Anti-PPP2R5C"
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. Protein function: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The PP2A-PPP2R5C holoenzyme may specifically dephosphorylate and activate TP53 and play a role in DNA damage- induced inhibition of cell proliferation. PP2A-PPP2R5C may also regulate the ERK signaling pathway through ERK dephosphorylation. [The UniProt Consortium]
Keywords: | Anti-PPP2R5C, Anti-KIAA0044, Anti-PP2A B subunit isoform B'-gamma, Anti-PP2A B subunit isoform R5-gamma, Anti-PP2A B subunit isoform B56-gamma, Anti-Renal carcinoma antigen NY-REN-29, Anti-PP2A B subunit isoform PR61-gamma, PPP2R5C Polyclonal Antibody |
Supplier: | Elabscience |
Supplier-Nr: | E-AB-62878 |
Properties
Application: | WB, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Recombinant protein of human PPP2R5C |
Database Information
KEGG ID : | K11584 | Matching products |
UniProt ID : | Q13362 | Matching products |
Gene ID | GeneID 5527 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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