Anti-POLA2

Anti-POLA2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-CAB3400.20 20 µl -

9 - 20 business days*

149.00€
 
Protein function: Accessory subunit of the DNA polymerase alpha complex (also known as the alpha... more
Product information "Anti-POLA2"
Protein function: Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis (PubMed:9705292). During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit POLA1, an accessory subunit POLA2 and two primase subunits, the catalytic subunit PRIM1 and the regulatory subunit PRIM2) is recruited to DNA at the replicative forks via direct interactions with MCM10 and WDHD1. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. These primers are initially extended by the polymerase alpha catalytic subunit and subsequently transferred to polymerase delta and polymerase epsilon for processive synthesis on the lagging and leading strand, respectively. [The UniProt Consortium]
Keywords: Anti-POLA2, Anti-DNA polymerase alpha subunit B, Anti-DNA polymerase alpha 70 kDa subunit
Supplier: Assay Genie
Supplier-Nr: CAB3400

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-POLA2"
Write a review
or to review a product.
Viewed