Anti-PINK1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-R35272-100UG	100 µg		-	-	3 - 10 business days*		755.00€

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0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s)... more

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Product information "Anti-PINK1"

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: PTEN induced putative kinase 1 Protein function: Protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) by mediating activation and translocation of PARK2. Targets PARK2 to dysfunctional depolarized mitochondria through the phosphorylation of MFN2. Activates PARK2 in 2 steps: (1) by mediating phosphorylation at 'Ser-65' of PARK2 and (2) mediating phosphorylation of ubiquitin, converting PARK2 to its fully-active form (PubMed:24660806, PubMed:24751536, PubMed:24784582, PubMed:25527291). [The UniProt Consortium]

Keywords:	Anti-BRPK, Anti-PINK1, Anti-PTEN-induced putative kinase protein 1, Anti-Serine/threonine-protein kinase PINK1, mitochondrial, PINK1 Antibody
Supplier:	NSJ Bioreagents
Supplier-Nr:	R35272

Properties

Application:	WB, ELISA (peptide)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Goat
Species reactivity:	human, mouse, rat
Immunogen:	Amino acids QGKAHLESRSYQEAQ were used as the immunogen for this PINK1 antibody.
Format:	Purified