Anti-PINK1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG55419.100	100 µl		-	-	6 - 14 business days*		584.00€

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Protein function: Protects against mitochondrial dysfunction during cellular stress by... more

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Product information "Anti-PINK1"

Protein function: Protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) by mediating activation and translocation of PARK2. Targets PARK2 to dysfunctional depolarized mitochondria through the phosphorylation of MFN2. Activates PARK2 in 2 steps: (1) by mediating phosphorylation at 'Ser-65' of PARK2 and (2) mediating phosphorylation of ubiquitin, converting PARK2 to its fully-active form (PubMed:24660806, PubMed:24751536, PubMed:24784582, PubMed:25527291). [The UniProt Consortium]

Keywords:	Anti-BRPK, Anti-PINK1, Anti-PTEN-induced putative kinase protein 1, Anti-Serine/threonine-protein kinase PINK1, mitochondrial
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG55419

Properties

Application:	WB, IHC (paraffin), ICC, IF
Antibody Type:	Monoclonal
Conjugate:	No
Host:	Mouse
Species reactivity:	human, mouse, rat
Immunogen:	Recombinant Human PINK1 protein
Format:	Purified