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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG11045.100 | 100 µg | - | - |
6 - 14 business days* |
624.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Promotes microtubule assembly and stability, and might be involved in the... more
Product information "Anti-phospho-Tau (Thr181), clone 2A4"
Protein function: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. [The UniProt Consortium]
| Keywords: | Anti-phospho-MAPT, Anti-phospho-MAPTL, Anti-phospho-PHF-tau, Anti-phospho-Paired helical filament-tau, Anti-phospho-Neurofibrillary tangle protein, Anti-phospho-Microtubule-associated protein tau |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG11045 |
Properties
| Application: | WB |
| Antibody Type: | Monoclonal |
| Clone: | 2A4 |
| Conjugate: | No |
| Host: | Mouse |
| Species reactivity: | human, mouse |
| Immunogen: | KLH-conjugated synthetic phosphopeptide around aa. 177-187 of Tau protein. (APKT(p)PPSSGEC) |
| Format: | Purified |
Database Information
| KEGG ID : | K04380 | Matching products |
| UniProt ID : | P10636 | Matching products |
| Gene ID | GeneID 4137 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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