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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| G-CABP0843.50 | 50 µl | - | - |
9 - 20 business days* |
352.00€
|
||
| G-CABP0843.100 | 100 µl | - |
9 - 20 business days* |
448.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
WB 1:500 - 1:2000. Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin from an... more
Product information "Anti-phospho-NEDD4L (Ser448)"
WB 1:500 - 1:2000. Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits TGF-beta signaling by triggering SMAD2 and TGFBR1 ubiquitination and proteasome-dependent degradation. Promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, SCN2A/Nav1.2, SCN3A/Nav1.3, SCN5A/Nav1.5, SCN9A/Nav1.7, SCN10A/Nav1.8, KCNA3/Kv1.3, KCNH2, EAAT1, KCNQ2/Kv7.2, KCNQ3/Kv7.3 or CLC5 (PubMed:26363003, PubMed:27445338). Promotes ubiquitination and degradation of SGK1 and TNK2. Ubiquitinates BRAT1 and this ubiquitination is enhanced in the presence of NDFIP1 (PubMed:25631046). Plays a role in dendrite formation by melanocytes (PubMed:23999003). Involved in the regulation of TOR signaling (PubMed:27694961). Ubiquitinates and regulates protein levels of NTRK1 once this one is activated by NGF (PubMed:27445338). [The UniProt Consortium]
| Keywords: | Anti-phospho-NEDD4L, Anti-phospho-Nedd4-2, Anti-phospho-NEDD4.2, Anti-phospho-KIAA0439, EC=2.3.2.26, Anti-phospho-E3 ubiquitin-protein ligase NEDD4-like, Anti-phospho-HECT-type E3 ubiquitin transferase NED4L, Phospho-NEDD4L-S448 pAb (CABP0843) |
| Supplier: | Assay Genie |
| Supplier-Nr: | CABP0843 |
Properties
| Application: | WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
| Immunogen: | A synthetic phosphorylated peptide around S448 of human NEDD4L (NP_001138439.1). |
Database Information
| KEGG ID : | K13305 | Matching products |
| UniProt ID : | Q96PU5 | Matching products |
| Gene ID | GeneID 23327 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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