Anti-phospho-4E-BP1 (Thr70)

Anti-phospho-4E-BP1 (Thr70)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG58238.50 50 µl - -

6 - 14 business days*

520.00€
 
Protein function: Repressor of translation initiation that regulates EIF4E activity by preventing... more
Product information "Anti-phospho-4E-BP1 (Thr70)"
Protein function: Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways. [The UniProt Consortium]
Keywords: Anti-phospho-4E-BP1, Anti-phospho-PHAS-I, Anti-phospho-EIF4EBP1, Anti-phospho-eIF4E-binding protein 1, Anti-phospho-Eukaryotic translation initiation factor 4E-binding protein 1
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG58238

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Phospho specific peptide corresponding to residues surrounding Thr70 of Human 4E-BP1
MW: 12 kD
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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