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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The protein encoded by this gene belongs to a family of bifunctional proteins that are involved... more
Product information "Anti-PFKFB3"
The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Protein function: Synthesis and degradation of fructose 2,6-bisphosphate. [The UniProt Consortium]
Keywords: | Anti-PFKFB3, Anti-iPFK-2, EC=3.1.3.46, EC=2.7.1.105, Anti-PFK/FBPase 3, Anti-6PF-2-K/Fru-2,6-P2ase 3, Anti-6-phosphofructo-2-kinase, Anti-Fructose-2,6-bisphosphatase, Anti-Renal carcinoma antigen NY-REN-56, Anti-6PF-2-K/Fru-2, PFKFB3 Polyclonal Antibody |
Supplier: | Elabscience |
Supplier-Nr: | E-AB-67803 |
Properties
Application: | IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | A synthetic peptide of human PFKFB3 (NP_004557.1). |
Database Information
KEGG ID : | K01103 | Matching products |
UniProt ID : | Q16875 | Matching products |
Gene ID | GeneID 5209 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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