36 products were found matching "K01103"!

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3PO
3PO

Item number: Cay19276-5

3PO is a competitive inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphate 3 (PFKFB3, IC50 = 23 µM) that causes a rapid reduction in fructose-2,6-bisphosphate (F2,6BP), glucose uptake, and lactate secretion. This is followed by a reduction in the steady-state concentration of ATP and NADH, resulting in...
Keywords: 3-(3-pyridinyl)-1-(4-pyridinyl)-2E-propen-1-one
Application: PFKFB3 inhibitor
CAS 18550-98-6
MW: 210.2 D
From 50.00€ *
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PFK158
PFK158

Item number: Cay22987-5

PFK158 is an inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3, IC50 = 137 nM for human recombinant PFKFB3). It inhibits PFKFB3 and glycolysis in Jurkat cells (IC50s = 1.6 and 0.847 µM, respectively). PFK158 inhibits the growth of leukemia cells in vitro (IC50 = 0.33 µM for Jurkat cells)...
Keywords: 1-(4-pyridinyl)-3-[7-(trifluoromethyl)-2E-quinolinyl]-2-propen-1-one
Application: PFKFB3 inhibitor
CAS 1462249-75-7
MW: 328.3 D
From 77.00€ *
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PFK15
PFK15

Item number: Cay17689-5

6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) is a bifunctional enzyme that contains distinct domains for the phosphorylation of fructose 6-phosphate and the dephosphorylation of fructose 2,6-bisphosphate. PFKFB3 protein expression is elevated in most tumor types. PFK15 is a selective inhibitor of...
Keywords: 1-(4-pyridinyl)-3-(2-quinolinyl)-2-propen-1-one
Application: PFKFB3 inhibitor
CAS 4382-63-2
MW: 260.3 D
From 60.00€ *
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YZ9
YZ9

Item number: Cay15352-5

Cells that are rapidly proliferating or hypoxic emphasize glycolysis over oxidative phosphorylation to meet energy needs. During glycolysis, fructose 6-phosphate (F6P) is phosphorylated by 6-phosphofructo-2-kinases (PFKs) to generate fructose 2,6-bisphosphate. As PFK family members also mediate the reverse reaction...
Keywords: 7-hydroxycoumarin-3-Carboxylic Acid ethyl ester, 7-hydroxy-2-ozo-2H-1-benzopyran-3-carboxylic acid, ethyl ester
Application: PFKFB3 inhibitor
CAS 6093-71-6
MW: 234.2 D
From 43.00€ *
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Anti-PFKFB3
Anti-PFKFB3

Item number: A304-248A

Protein function: Synthesis and degradation of fructose 2,6-bisphosphate. [The UniProt Consortium]
Keywords: Anti-iPFK-2, Anti-PFKFB3, EC=3.1.3.46, EC=2.7.1.105, Anti-PFK/FBPase 3, Anti-6PF-2-K/Fru-2,6-P2ase 3,...
Application: WB, IP
Host: Rabbit
Species reactivity: human
From 164.00€ *
Review
Anti-PFKFB3
Anti-PFKFB3

Item number: A304-249A

Protein function: Synthesis and degradation of fructose 2,6-bisphosphate. [The UniProt Consortium]
Keywords: Anti-iPFK-2, Anti-PFKFB3, EC=3.1.3.46, EC=2.7.1.105, Anti-PFK/FBPase 3, Anti-6PF-2-K/Fru-2,6-P2ase 3,...
Application: WB, IP
Host: Rabbit
Species reactivity: human
From 164.00€ *
Review
PFKFB3, human recombinant protein, N-terminal His-tag
PFKFB3, human recombinant protein, N-terminal His-tag

Item number: BPS-71089

Human 6-phosphofructo-2-kinase/ fructose-2,6-biphosphatase 3, also known as PFKFB3 and IPFK2, (GenBank Accession No. NM_004566), amino acids 2-520(end)) with N-terminal His-tag, MW = 60.4 kDa, expressed in an E. coli cell expression system.
Keywords: PFKFB3, iPFK-2, PFK/FBPase 3, 6PF-2-K/Fru-2,6-P2ase 3, 6-phosphofructo-2-kinase, Fructose-2,6-bisphosphatase, Renal...
Application: Enzyme kinetics, inhibitor screening, selectivity profiling
Expressed in: E.coli
Origin: human
MW: 60.4 kD
547.00€ *
Review
Anti-PFKFB3
Anti-PFKFB3

Item number: NSJ-F51072-0.08ML

In 1X PBS, pH 7.4, with 0.09% sodium azide. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells,...
Keywords: Anti-iPFK-2, Anti-PFKFB3, EC=3.1.3.46, EC=2.7.1.105, Anti-PFK/FBPase 3, Anti-6PF-2-K/Fru-2,6-P2ase 3,...
Application: WB, IHC, ELISA
Host: Rabbit
Species reactivity: human
From 326.00€ *
Review
Anti-PFKFB3
Anti-PFKFB3

Item number: ARG54872.100

Protein function: Synthesis and degradation of fructose 2,6-bisphosphate. [The UniProt Consortium]
Keywords: Anti-PFKFB3, Anti-iPFK-2, EC=3.1.3.46, Anti-PFK/FBPase 3, EC=2.7.1.105, Anti-6PF-2-K/Fru-2,6-P2ase 3,...
Application: IHC (paraffin), WB
Host: Rabbit
Species reactivity: human
624.00€ *
Review
Anti-PFKFB3
Anti-PFKFB3

Item number: E-AB-19543.120

The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of...
Keywords: Anti-PFKFB3, Anti-iPFK-2, EC=3.1.3.46, Anti-PFK/FBPase 3, EC=2.7.1.105, Anti-6PF-2-K/Fru-2,6-P2ase 3,...
Application: WB, ELISA
Host: Rabbit
Species reactivity: human, rat
From 71.00€ *
Review
Anti-PFKFB3
Anti-PFKFB3

Item number: E-AB-53523.120

The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of...
Keywords: Anti-PFKFB3, Anti-iPFK-2, EC=3.1.3.46, Anti-PFK/FBPase 3, EC=2.7.1.105, Anti-6PF-2-K/Fru-2,6-P2ase 3,...
Application: WB, ELISA
Host: Rabbit
Species reactivity: human, rat
From 71.00€ *
Review
Anti-PFKFB3
Anti-PFKFB3

Item number: E-AB-66342.120

The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of...
Keywords: Anti-PFKFB3, Anti-iPFK-2, EC=3.1.3.46, EC=2.7.1.105, Anti-PFK/FBPase 3, Anti-6PF-2-K/Fru-2,6-P2ase 3,...
Application: IF
Host: Rabbit
Species reactivity: human, mouse
From 198.00€ *
Review
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