Anti-PDLIM4

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-15349.20 20 µl -

7 - 16 business days*

71.00€
E-AB-15349.60 60 µl -

7 - 16 business days*

143.00€
E-AB-15349.120 120 µl -

7 - 16 business days*

238.00€
E-AB-15349.200 200 µl -

7 - 16 business days*

396.00€
 
This gene encodes a protein which may be involved in bone development. Mutations in this gene are... more
Product information "Anti-PDLIM4"
This gene encodes a protein which may be involved in bone development. Mutations in this gene are associated with susceptibility to osteoporosis. Protein function: Isoform 1: Suppresses SRC activation by recognizing and binding to active SRC and facilitating PTPN13-mediated dephosphorylation of SRC 'Tyr-419' leading to its inactivation. Inactivated SRC dissociates from this protein allowing the initiation of a new SRC inactivation cycle (PubMed:19307596). Involved in reorganization of the actin cytoskeleton (PubMed:21636573). In nonmuscle cells, binds to ACTN1 (alpha- actinin-1), increases the affinity of ACTN1 to F-actin (filamentous actin), and promotes formation of actin stress fibers. Involved in regulation of the synaptic AMPA receptor transport in dendritic spines of hippocampal pyramidal neurons directing the receptors toward an insertion at the postsynaptic membrane. Links endosomal surface-internalized GRIA1-containing AMPA receptors to the alpha-actinin/actin cytoskeleton. Increases AMPA receptor-mediated excitatory postsynaptic currents in neurons. [The UniProt Consortium]
Keywords: Anti-RIL, Anti-PDLIM4, Anti-LIM protein RIL, Anti-PDZ and LIM domain protein 4, Anti-Reversion-induced LIM protein, PDLIM4 Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-15349

Properties

Application: WB, IHC, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Recombinant protein of human PDLIM4
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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