Anti-PDLIM4

Anti-PDLIM4
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R33674-100UG 100 µg - -

3 - 10 business days*

755.00€
 
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s)... more
Product information "Anti-PDLIM4"
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: PDZ and LIM domain 4 Protein function: [Isoform 1]: Suppresses SRC activation by recognizing and binding to active SRC and facilitating PTPN13-mediated dephosphorylation of SRC 'Tyr-419' leading to its inactivation. Inactivated SRC dissociates from this protein allowing the initiation of a new SRC inactivation cycle (PubMed:19307596). Involved in reorganization of the actin cytoskeleton (PubMed:21636573). In nonmuscle cells, binds to ACTN1 (alpha-actinin-1), increases the affinity of ACTN1 to F-actin (filamentous actin), and promotes formation of actin stress fibers. Involved in regulation of the synaptic AMPA receptor transport in dendritic spines of hippocampal pyramidal neurons directing the receptors toward an insertion at the postsynaptic membrane. Links endosomal surface-internalized GRIA1- containing AMPA receptors to the alpha-actinin/actin cytoskeleton. Increases AMPA receptor-mediated excitatory postsynaptic currents in neurons. [The UniProt Consortium]
Keywords: Anti-RIL, Anti-PDLIM4, Anti-LIM protein RIL, Anti-PDZ and LIM domain protein 4, Anti-Reversion-induced LIM protein, PDLIM4 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: R33674

Properties

Application: WB, IHC (paraffin), ELISA (peptide)
Antibody Type: Polyclonal
Conjugate: No
Host: Goat
Species reactivity: human
Immunogen: Amino acids DVVAVYPNAKVELV
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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