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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES11924.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES11924.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The protein encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an... more
Product information "Anti-PCNT"
The protein encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an integral component of the pericentriolar material (PCM). The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus. The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes, cytoskeleton, and cell-cycle progression. Mutations in this gene cause Seckel syndrome-4 and microcephalic osteodysplastic primordial dwarfism type II. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015], Protein function: Integral component of the filamentous matrix of the centrosome involved in the initial establishment of organized microtubule arrays in both mitosis and meiosis. Plays a role, together with DISC1, in the microtubule network formation. Is an integral component of the pericentriolar material (PCM). May play an important role in preventing premature centrosome splitting during interphase by inhibiting NEK2 kinase activity at the centrosome. [The UniProt Consortium] Recommended dilutions: IHC-p 1:50-300. Cellular localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Centrosomal at all stages of the cell cycle. Remains associated with centrosomes following microtubule depolymerization. Colocalized with DISC1 at the centrosome.
Keywords: | Anti-PCNT, Anti-Kendrin, Anti-KIAA0402, Anti-Pericentrin, Anti-Pericentrin-B, PCNT rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES11924 |
Properties
Application: | IHC, IF |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | Synthesized peptide derived from part region of human protein |
MW: | 366 kD |
Format: | Purified |
Database Information
KEGG ID : | K16481 | Matching products |
UniProt ID : | O95613 | Matching products |
Gene ID | GeneID 5116 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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