Anti-PCGF6

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG40118.100	100 µl		-	-	6 - 14 business days*		584.00€

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Protein function: Transcriptional repressor (PubMed:12167161). May modulate the levels of histone... more

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Product information "Anti-PCGF6"

Protein function: Transcriptional repressor (PubMed:12167161). May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase (PubMed:17320162). Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (PubMed:12167161). Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity (PubMed:26151332). [The UniProt Consortium]

Keywords:	Anti-MBLR, Anti-PCGF6, Anti-RING finger protein 134, Anti-Mel18 and Bmi1-like RING finger, Anti-Polycomb group RING finger protein 6
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG40118

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, rat (Expected: mouse)
Immunogen:	KLH-conjugated synthetic peptide corresponding to aa. 190-217 of Human PCGF6
MW:	39 kD
Format:	Purified