Anti-PARP-2 (Poly ADP-Ribose Polymerase-2)

Poly(ADP-ribose) polymerase 1, (PARP-1) and poly(ADP-ribose) polymerase 2 (PARP-2) catalyze the formation of poly(ADP-ribose) polymers in a DNA-dependent manner. PARP-2 displays automodi?cation properties similar to PARP-1. These act by poly(ADP-ribosylation), which is a post-translational modi?cation of nuclear proteins in response to DNA damage that activates the base excision repair machinery. Applications: Suitable for use in Western Blot and ELISA. Other applications have not been tested. Recommended Dilution: Western Blot: 1:250-1:500, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.