Anti-PARD3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA030443.25	25 µl		-		7 - 10 business days*		300.00€
ATA-HPA030443.100	100 µl		-		7 - 10 business days*		421.00€

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Protein function: Adapter protein involved in asymmetrical cell division and cell polarization... more

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Product information "Anti-PARD3"

Protein function: Adapter protein involved in asymmetrical cell division and cell polarization processes (PubMed:27925688, PubMed:10954424). Seems to play a central role in the formation of epithelial tight junctions (PubMed:27925688). Targets the phosphatase PTEN to cell junctions. Involved in Schwann cell peripheral myelination. Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins (PubMed:10934474). Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons (PubMed:19812038, PubMed:27925688). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 80% and to rat: 79%

Keywords:	Anti-PAR3, Anti-ASIP, Anti-PAR-3, Anti-PARD-3, Anti-PAR3-alpha, Anti-CTCL tumor antigen se2-5, Anti-Partitioning defective 3 homolog, Anti-Atypical PKC isotype-specific-interacting protein
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA030443

Properties

Application:	ICC, IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: LKGLGDMFRI QAKTREFRER QARERDYAEI QDFHRTFGCD DELMYGGVSS YEGSMALNAR PQSPREGHMM DALYAQVKKP RNSKPSPVDS NR (ATA-APrEST77452)