Anti-PAK7/PAK6 (PACO03032)

PAK7/PAK6 Antibody from Assay Genie with reactivity against Human, Mouse and for use in ELISA, WB applications. PAK7/PAK6 Antibody is Polyclonal and is a IgG isotype antibody from Assay Genie.. Protein function: Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, proliferation or cell survival. Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates the proto-oncogene RAF1 and stimulates its kinase activity. Promotes cell survival by phosphorylating the BCL2 antagonist of cell death BAD. Phosphorylates CTNND1, probably to regulate cytoskeletal organization and cell morphology. Keeps microtubules stable through MARK2 inhibition and destabilizes the F-actin network leading to the disappearance of stress fibers and focal adhesions. [The UniProt Consortium]