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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES10010.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES10010.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
function:May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the... more
Product information "Anti-PAIRB"
function:May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay.,subcellular location:Also found in perinuclear regions.,subunit:Interacts with CHD3 and TDRD3.,tissue specificity:Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain., Protein function: Ribosome-binding protein that promotes ribosome hibernation, a process during which ribosomes are stabilized in an inactive state and preserved from proteasomal degradation (PubMed:36691768). Acts via its association with EEF2/eEF2 factor, sequestering EEF2/eEF2 at the A- site of the ribosome and promoting ribosome stabilization and storage in an inactive state. May also play a role in the regulation of mRNA stability: binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay (PubMed:11001948). Seems to play a role in PML-nuclear bodies formation (PubMed:28695742). [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000. Cellular localization: Cytoplasm . Nucleus . Cytoplasm, perinuclear region .
Keywords: | Anti-PAIRBP1, Anti-PAI-RBP1, Anti-PAI1 RNA-binding protein 1, Anti-SERPINE1 mRNA-binding protein 1, Anti-Plasminogen activator inhibitor 1 RNA-binding protein, PAIRB rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES10010 |
Properties
Application: | WB, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, rat, mouse |
Immunogen: | Synthesized peptide derived from human protein . at AA range: 60-140 |
MW: | 44 kD |
Format: | Purified |
Database Information
KEGG ID : | K13199 | Matching products |
UniProt ID : | Q8NC51 | Matching products |
Gene ID | GeneID 26135 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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