Anti-PABPN1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A303-524A-T	10 µl (2 µg)		-		2 - 8 business days*		164.00€
A303-524A	100 µl		-		2 - 8 business days*		588.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Involved in the 3'-end formation of mRNA precursors (pre-mRNA) by the addition... more

Close menu

Product information "Anti-PABPN1"

Protein function: Involved in the 3'-end formation of mRNA precursors (pre-mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product. Stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and controls also the poly(A) tail length. Increases the affinity of poly(A) polymerase for RNA. Is also present at various stages of mRNA metabolism including nucleocytoplasmic trafficking and nonsense-mediated decay (NMD) of mRNA. Cooperates with SKIP to synergistically activate E-box-mediated transcription through MYOD1 and may regulate the expression of muscle-specific genes. Binds to poly(A) and to poly(G) with high affinity. May protect the poly(A) tail from degradation. [The UniProt Consortium]

Keywords:	Anti-PAB2, Anti-PABII, Anti-PABP-2, Anti-PABPN1, Anti-Poly(A)-binding protein 2, Anti-Poly(A)-binding protein II, Anti-Polyadenylate-binding protein 2, Anti-Nuclear poly(A)-binding protein 1, Anti-Polyadenylate-binding nuclear protein 1
Supplier:	Bethyl Laboratories
Supplier-Nr:	A303-524A

Properties

Application:	WB, IP, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: dog, pig, orangutan, rhesus monkey, gorilla, chimpanzee, white-tufted-ear marmoset, gray short-tailed opossum, small-eared galago, thirteen-lined ground squirrel, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A303-524A-T maps to a region between residue 100 and 150 of human Poly(A) Binding Protein, Nuclear 1 using the numbering given in entry NP_004634.1 (GeneID 8106).
Format:	Antigen Affinity Purified