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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
BOT-BNUM1925-50 | 50 µl | - |
Request delivery time estimate |
565.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The specificity of this monoclonal antibody to its intended target was validated by HuProt(TM)... more
Product information "Anti-p53 Tumor Suppressor Protein (PCRP-TP53-1F7), BSA-free, 1 mg/mL"
The specificity of this monoclonal antibody to its intended target was validated by HuProt(TM) Array, containing more than 19,000, full-length human proteins. Recognizes a 53 kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53 protein. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia. Mutations involving p53 are found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.Primary antibodies are available purified, or with a selection of fluorescent CF(R) Dyes and other labels. CF(R) Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF(R)405S and CF(R)405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors. Concentration: 1 mg/mL Storage buffer: PBS, no BSA, no azide
Keywords: | p53 Tumor Suppressor Protein (PCRP-TP53-1F7), BSA-free, 1 mg/mL, |
Supplier: | Biotium |
Supplier-Nr: | BNUM1925 |
Properties
Application: | IHC (paraffin) (verif.) |
Conjugate: | No |
Format: | Purified, BSA-free |
Database Information
Handling & Safety
Storage: | +20°C |
Shipping: | +20°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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