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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
P1001-26D2.100 | 100 µg | - | - |
3 - 19 business days* |
575.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
p53 is a 339 amino acid protein (53kD) that is thought to act as a tumor suppressor gene. p53 is... more
Product information "Anti-p53 (Tumor Suppressor Protein, Oncogene Protein), clone 3G227"
p53 is a 339 amino acid protein (53kD) that is thought to act as a tumor suppressor gene. p53 is a DNA-binding protein, and missense mutation of the gene can lead to loss of its DNA-binding functions, and subsequent inactivation of p53 may be a contributing factor in tumorigenesis. Mutation of p53 occurs at many sites and represents a common genetic alteration in human malignancy. Mutations which result in overexpression of p53 can be detected by immunohistochemistry, and overexpression and accumulation of p53 in cell nucleus was reported for a number of human tumors, such as breast, lung and colon carcinomas. Staining of p53 overexpression may be a useful tumor and prognostic marker. Applications: Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: ~1:1000, Immunoprecipitation (Native): ~2-5ug, Immunohistochemistry (Frozen or PE): ~1:50-100, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Supplier: | United States Biological |
Supplier-Nr: | P1001-26D2 |
Properties
Application: | IHC, IP, WB |
Antibody Type: | Monoclonal |
Clone: | 3G227 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Format: | Purified |
Database Information
KEGG ID : | K04451 | Matching products |
UniProt ID : | P04637 | Matching products |
Gene ID | GeneID 7157 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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