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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
P1003-15E.100 | 100 µg | - | - |
3 - 19 business days* |
537.00€
|
||
P1003-15E.250 | 250 µg | - | - |
3 - 19 business days* |
750.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Purinoceptor 7 is also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal... more
Product information "Anti-P2X7 Receptor (P2X Purinoceptor 7, P2rx7, P2X7, P2X(7), P2X7R, AI467586, ATP Receptor, P2Z Rece"
Purinoceptor 7 is also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal tail with multiple potential protein and lipid interaction motifs and is highly polymorphic. It is a cation selective ion channel that opens up on binding of extracellular ATP. Sustained activation by extracellular ATP results in the formation of a reversible pore in the plasma membrane that is permeable to hydrophilic solutes of up to 900 Da. Once a pore is opened massive upset of cytoplasmic ion homeostasis occurs and the pore stays open as long as it is bound by ATP. Should ATP stimulation continue the cell will become irreversibly damaged and die. P2X7 plays a key role in the maturation and release of IL-1 and other IL-1 family members during inflammation. As such, P2X7 blockers might be useful as anti-inflammatory agents. Applications: Suitable for use in Flow cytometry and Immunofluorescence. Other applications have not been tested. , Recommended Dilutions: Flow cytometry: 1:25-1:100. Use 10ul of the suggested working dilution to label 10e6 cells in 100ul., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: | United States Biological |
Supplier-Nr: | P1003-15E |
Properties
Application: | FC, IF |
Antibody Type: | Monoclonal |
Clone: | Hano43 |
Conjugate: | No |
Host: | Rat |
Species reactivity: | mouse |
Immunogen: | A P2X7-expression construct and a final boost with P2X7-transfected HEK cells. |
Format: | Affinity Purified |
Database Information
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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