Anti-p16INK4a/CDKN2 Antibody(Clone: DCS-50)

Anti-p16INK4a/CDKN2 Antibody(Clone: DCS-50)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABE-39-1078-100 100 µg -

3 - 11 business days*

801.00€
 
p16(INK4A), also known as cyclin-dependent kinase inhibitor 2A(CDKN2A), or multiple tumor... more
Product information "Anti-p16INK4a/CDKN2 Antibody(Clone: DCS-50)"
p16(INK4A), also known as cyclin-dependent kinase inhibitor 2A(CDKN2A), or multiple tumor suppressor 1(MTS1). The p16 gene(CDKN2A) was mapped to 9p21. The p16 gene encodes a negative regulator of the cell cycle. CDKN2 plays an important role during tumorigenesis or tumor progression in a significant proportion of pancreatic adenocarcinomas. Germ-line mutations in the CDKN2A tumor-suppressor gene have been linked to the development of melanoma in some families with inherited melanoma. Protein function: Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein. [The UniProt Consortium]
Keywords: Anti-p16, Anti-CDK4I, Anti-p16-INK4, Anti-p16-INK4a, Anti-Cyclin-dependent kinase inhibitor 2A, Anti-Cyclin-dependent kinase 4 inhibitor A, Monoclonal Antibody to Anti-p16INK4a/CDKN2 Antibody(Clone: DCS-50)
Supplier: Abeomics
Supplier-Nr: 39-1078

Properties

Application: WB, IHC-F, ICC
Antibody Type: Monoclonal
Clone: DCS-50
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Recombinant human p16 protein.

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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