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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V5085-20UG | 20 µg | - | - |
3 - 10 business days* |
332.00€
|
||
NSJ-V5085-100UG | 100 µg | - | - |
3 - 10 business days* |
752.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Occludin is a tetraspan... more
Product information "Anti-Occludin, clone OCLN/2182"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Occludin is a tetraspan integral membrane protein in epithelial and endothelial tight junction (TJ) structures that can contain two extracellular loops. The protein exists in a variety of phosphorylated forms. Phosphorylation is involved in regulating both the localization and the function of Occludin. Expression of Occludin is upregulated by polyunsaturated fatty acids, increasing trans-endothelial cell resistance and reducing cellular permeability to large molecules. The level of Occludin varies greatly depending on tissue, in brain tissue, Occludin is highly expressed at cell-cell contact sites. Non-neural tissues show lower expression and discontinuous distribution. Up-regulation of epithelial Occludin may play a role in enhancing paracellular permeability and be related to the damage to the tight junction. Protein function: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. It is able to induce adhesion when expressed in cells lacking tight junctions. [The UniProt Consortium]
Keywords: | Anti-OCLN, Anti-Occludin, Occludin Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V5085 |
Properties
Application: | IHC (paraffin) |
Antibody Type: | Monoclonal |
Clone: | OCLN/2182 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | A recombinant human protein fragment (within amino acids 282-415) |
Format: | Purified |
Database Information
KEGG ID : | K06088 | Matching products |
UniProt ID : | Q16625 | Matching products |
Gene ID | GeneID 100506658 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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