Anti-NXF1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA061593.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA061593.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Involved in the nuclear export of mRNA species bearing retroviral constitutive... more

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Product information "Anti-NXF1"

Protein function: Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway) (PubMed:10924507). The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex (PubMed:18364396, PubMed:19165146, PubMed:9660949). ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export (PubMed:18364396, PubMed:19165146, PubMed:9660949). Also involved in nuclear export of m6A-containing mRNAs: interaction between SRSF3 and YTHDC1 facilitates m6A-containing mRNA-binding to both SRSF3 and NXF1, promoting mRNA nuclear export (PubMed:28984244). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 86% and to rat: 91%

Keywords:	Anti-TAP, Anti-NXF1, Anti-Tip-associated protein, Anti-mRNA export factor TAP, Anti-Tip-associating protein, Anti-Nuclear RNA export factor 1
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA061593

Properties

Application:	ICC, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: IRSSRLEEDD GDVAMSDAQD GPRVRYNPYT TRPNRRGDTW HDRDRIHVTV RRDRAPPERG GAGTSQDGTS KNWF (ATA-APrEST88256)