Anti-NUP35

Nucleoporin 35kDa (NUP35), also known as NUP 53 or Mitotic phosphoprotein 44 (MP44) is a phosphoprotein and a member of the nucleoporin family. It plays a vital role in the Nuclear Envelope and Nuclear Pore Complex assembly. NUP35 contains two membrane binding regions, is localized to the nuclear rim, and is part of the nuclear pore complex. Nup35 binds specifically to its interacting partner Nup155 and this interaction is critical for proper NPC and NE assembly. Protein function: Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. May play a role in the association of MAD1 with the NPC. [The UniProt Consortium]