Anti-NUDT5

Anti-NUDT5
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG44130.50 50 µg - -

6 - 14 business days*

520.00€
 
Protein function: Enzyme that can either act as an ADP-sugar pyrophosphatase in absence of... more
Product information "Anti-NUDT5"
Protein function: Enzyme that can either act as an ADP-sugar pyrophosphatase in absence of diphosphate or catalyze the synthesis of ATP in presence of diphosphate (PubMed:27257257). In absence of diphosphate, hydrolyzes with similar activities various modified nucleoside diphosphates such as ADP-ribose, ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP (PubMed:10567213, PubMed:10722730, PubMed:19699693, PubMed:21389046, PubMed:17052728). Can also hydrolyze other nucleotide sugars with low activity (PubMed:19699693, PubMed:21389046). In presence of diphosphate, mediates the synthesis of ATP in the nucleus by catalyzing the conversion of ADP-ribose to ATP and ribose 5-phosphate. Nuclear ATP synthesis takes place when dephosphorylated at Thr-45 (PubMed:27257257). Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming (PubMed:27257257). Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA. [The UniProt Consortium]
Keywords: Anti-NUDT5, Anti-YSA1H, Anti-YSA1H, Anti-hNUDT5, Anti-hNUDT5, Anti-Nudix motif 5, Anti-Nudix motif 5, Anti-8-oxo-dGDP phosphatase, Anti-8-oxo-dGDP phosphatase, Anti-ADP-sugar pyrophosphatase, Anti-ADP-sugar pyrophosphatase, Anti-Nuclear ATP-synthesis prot
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG44130

Properties

Application: FC, IHC (paraffin), WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, rat
Immunogen: Human NUDT5 recombinant protein (Position: M1-F219)
MW: 24 kD
Format: Antigen Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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