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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-30-1250-0.1 | 100 µg | - |
3 - 11 business days* |
653.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
NTAL (Non-T cell activation linker), also known as LAB (Linker for activation of B cells), is a... more
Product information "Anti-NTAL / LAB Monoclonal Antibody (Clone:NAP-07)"
NTAL (Non-T cell activation linker), also known as LAB (Linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells and macrophages. It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells. However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function. Protein function: Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2. [The UniProt Consortium]
Keywords: | Anti-LAB, Anti-LAT2, Anti-HSPC046, Anti-Non-T-cell activation linker, Anti-Linker for activation of B-cells, Anti-Membrane-associated adapter molecule, Anti-Linker for activation of T-cells family member 2, Anti-NTAL / LAB Monoclonal Antibody (Clone:NAP-0 |
Supplier: | Abeomics |
Supplier-Nr: | 30-1250 |
Properties
Application: | FC, IP, WB, ICC |
Antibody Type: | Monoclonal |
Clone: | NAP-07 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | mouse, human |
Immunogen: | Recombinant cytoplasmic domain (aa 91-243) of human NTAL. |
Format: | Affinity Purified |
Database Information
UniProt ID : | Q9GZY6 | Matching products |
Gene ID | GeneID 7462 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
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