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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ARG43152.100 | 100 µl | - | - |
6 - 14 business days* |
624.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated... more
Product information "Anti-NPLOC4"
Protein function: The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. Acts as a negative regulator of type I interferon production via the complex formed with VCP and UFD1, which binds to DDX58/RIG-I and recruits RNF125 to promote ubiquitination and degradation of DDX58/RIG-I (PubMed:26471729). [The UniProt Consortium]
Keywords: | Anti-NPLOC4, Anti-KIAA1499, Anti-Protein NPL4, Anti-Protein NPL4, Anti-Nuclear protein localization protein 4 homolog, Anti-Nuclear protein localization protein 4 homolog |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG43152 |
Properties
Application: | ICC, IF, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse (Expected: rat) |
Immunogen: | Recombinant fusion protein corresponding to aa. 1-270 of Human NPLOC4 (NP_060391.2) |
MW: | 68 kD |
Format: | Affinity Purified |
Database Information
KEGG ID : | K14015 | Matching products |
UniProt ID : | Q8TAT6 | Matching products |
Gene ID | GeneID 55666 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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