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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
N2700-03B.25 | 25 µg | - | - |
3 - 19 business days* |
427.00€
|
||
N2700-03B.100 | 100 µg | - | - |
3 - 19 business days* |
673.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein tyrosine nitration results in a post-translational modification that is increasingly... more
Product information "Anti-Nitrotyrosine (nTyr)"
Protein tyrosine nitration results in a post-translational modification that is increasingly receiving attention as an important component of nitric oxide signaling (2). While multiple nonenzymatic mechanisms are known to be capable of producing nitrated tyrosine residues, most tyrosine nitration events involve catalysis by metalloproteins such as myeloperoxidase, eosinophilperoxidase (3), myoglobin, the cytochrome P-450s, superoxide dismutase and prostacyclin synthase. , Nitrotyrosine may also serve as a biomarker for the effects of reactive nitrogen oxides, based on tyrosine residues becoming nitrated in proteins at sites of inflammation induced tissue injury (1). The presence of nitrotyrosine-containing proteins therefore has shown high correlation to disease states such as atherosclerosis, Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis (4). Applications: Suitable for use in Western Blot, ELISA, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.7ug/ml detects 5ug SIN-1 treated BSA using Goat anti-mouse IgG-HRP as the secondary antibody., Optimal dilutions to be determined by the researcher. Recommended Secondary Antibodies: I1904-06C: IgG, H&L (HRP) (X-Adsorbed) Pab Gt x Mo, I1904-06H: IgG, H&L (HRP) (X-Adsorbed) Pab Gt x Mo, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: | United States Biological |
Supplier-Nr: | N2700-03B |
Properties
Application: | ELISA, IHC, IP, WB |
Antibody Type: | Monoclonal |
Clone: | 7L25 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | dog, human, mouse, rat |
Immunogen: | 3-(4-Hydroxy-3-nitrophenyl acetamido) propionic acid-BSA conjugate. |
Format: | Affinity Purified |
Database Information
Handling & Safety
Storage: | +4°C (Glycerol) |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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