Anti-Neurotensin Receptor 2

0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Neurotensin is a central nervous system protein involved with the regulation and release of Luteinizing hormone (Lutropin), which regulates ovulation in females and testosterone production in males, and Prolactin (Luteotropin), which enables milk production in female mammals. The GPCR Neurotensin receptor 2 (NTSR2) is one of three receptors for Neurotensin (NTSR1-3). Unlike NTSR1, NTSR2 has only a low affinity for Neurotensin, but high affinity for levocabastine, a histamine H1 receptor antagonist that can block Neurotensin binding to NTSR2 but not affect its binding to NTSR1. Protein function: Receptor for the tridecapeptide neurotensin. It is associated with G proteins that activate a phosphatidylinositol- calcium second messenger system. [The UniProt Consortium]