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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
AG-27B-0018PF-C100 | 100 µg | - |
3 - 9 business days* |
385.00€
|
|||
AG-27B-0018PF-C500 | 500 µg | - |
3 - 9 business days* |
1,045.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Functional: Inhibits the activation of human and mouse Netrin-1 to human or mouse receptors DCC... more
Product information "Anti-Netrin-1 (human), clone 2F5, (rec.) (blocking) (preservative free)"
Functional: Inhibits the activation of human and mouse Netrin-1 to human or mouse receptors DCC or UNC5 (KD antibody-Netrin-1 is 1.5nM). Anti-Netrin-1 (human), mAb (rec.) (blocking) (2F5) is composed of human variable regions (VH and VL) (?-chain) of immunoglobulin fused to the human lgG2 Fc domain. Netrin-1 controls guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Netrin-1 is also involved in tumorigenesis by regulating apoptosis. Netrin-1 promotes atherosclerosis by retaining macrophages in the artery wall. Netrin-1 also governs induced pluripotent stem cell (iPS) formation and improves reprogramming efficiency of human and mouse somatic cells by limiting apoptosis mediated by Netrin-1 receptors DCC or UNC5b.
Keywords: | Anti-NTN1, Anti-NTN1L, Anti-Netrin-1, Anti-Epididymis tissue protein Li 131P |
Supplier: | AdipoGen Life Sciences |
Supplier-Nr: | AG-27B-0018PF |
Properties
Application: | ELISA, FA (blocking) |
Antibody Type: | Monoclonal |
Clone: | 2F5 |
Conjugate: | No |
Host: | Human |
Species reactivity: | human, mouse |
Immunogen: | Recombinant human Netrin-1. |
Purity: | >95% |
Format: | Purified |
Database Information
KEGG ID : | K06843 | Matching products |
UniProt ID : | O95631 | Matching products |
Gene ID | GeneID 9423 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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