Anti-NELFE

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA007187.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA007187.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Essential component of the NELF complex, a complex that negatively regulates... more

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Product information "Anti-NELFE"

Protein function: Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II (PubMed:10199401). The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex (PubMed:11940650, PubMed:12612062). Provides the strongest RNA binding activity of the NELF complex and may initially recruit the NELF complex to RNA (PubMed:18303858, PubMed:27282391). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 93% and to rat: 94%

Keywords:	Anti-RD, Anti-NELFE, Anti-NELF-E, Anti-RNA-binding protein RD, Anti-Negative elongation factor E
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA007187

Properties

Application:	IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: LLALKKQSSS STTSQGGVKR SLSEQPVMDT ATATEQAKQL VKSGAISAIK AETKNSGFKR SRTLEGKLKD PEKGPVPTFQ PFQRSISADD DLQESSRRPQ RKSLYESFVS SSDRLRELGP DG (ATA-APrEST71152)