Anti-NEIL2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA073916.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA073916.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Involved in base excision repair of DNA damaged by oxidation or by mutagenic... more

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Product information "Anti-NEIL2"

Protein function: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Has DNA glycosylase activity towards 5- hydroxyuracil and other oxidized derivatives of cytosine with a preference for mismatched double-stranded DNA (DNA bubbles). Has low or no DNA glycosylase activity towards thymine glycol, 2-hydroxyadenine, hypoxanthine and 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 74% and to rat: 76%

Keywords:	Anti-NEH2, Anti-NEIL2, EC=3.2.2.-, EC=4.2.99.18, Anti-Nei homolog 2, Anti-Nei-like protein 2, Anti-Endonuclease 8-like 2, Anti-Endonuclease VIII-like 2, Anti-DNA glycosylase/AP lyase Neil2, Anti-DNA-(apurinic or apyrimidinic site) lyase Neil2
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA073916

Properties

Application:	ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: IHPLSLGSVL SASRREVLVD HVVEFSTAWL QGKFQGRPQH TQVYQKEQCP AGHQVMKEAF GPEDGLQRLT WWCPQCQPQL SEEPEQCQFS (ATA-APrEST90083)