Anti-NECD

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ELK-ES19109.50	50 µl		-	-	Request delivery time estimate		169.00€
ELK-ES19109.100	100 µl		-	-	Request delivery time estimate		283.00€

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Protein function: Growth suppressor that facilitates the entry of the cell into cell cycle... more

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Product information "Anti-NECD"

Protein function: Growth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle-promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Also functions as a transcription factor and directly binds to specific guanosine-rich DNA sequences. [The UniProt Consortium] Recommended dilutions: WB 1:1000-2000. Cellular localization: Perikaryon. Nucleus. Neural perikarya, translocates to the nucleus of postmitotic neurons and interacts with the nuclear matrix.

Keywords:	Anti-NDN, Anti-Necdin, NECD rabbit pAb
Supplier:	ELK Biotechnology
Supplier-Nr:	ES19109

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	Synthesized peptide derived from human NECD AA range: 101-151
Format:	Purified

Database Information

KEGG ID :	K19482 \| Matching products
UniProt ID :	Q99608 \| Matching products
Gene ID	GeneID 4692 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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