Anti-NCOA4 (NCOA4, ARA70, ELE1, RFG, Nuclear receptor coactivator 4, Androgen receptor coactivator 7

This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:500~3200, Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.