Anti-NCBP3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA013195.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA013195.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Associates with NCBP1/CBP80 to form an alternative cap- binding complex (CBC)... more

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Product information "Anti-NCBP3"

Protein function: Associates with NCBP1/CBP80 to form an alternative cap- binding complex (CBC) which plays a key role in mRNA export. NCBP3 serves as adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80. Unlike the conventional CBC with NCBP2 which binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus, the alternative CBC with NCBP3 does not bind snRNA and associates only with mRNA thereby playing a role in only mRNA export. The alternative CBC is particularly important in cellular stress situations such as virus infections and the NCBP3 activity is critical to inhibit virus growth (PubMed:26382858). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 96% and to rat: 96%

Keywords:	Anti-C17orf85, Anti-Protein ELG, Anti-Nuclear cap-binding protein subunit 3
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA013195

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: EYPPAHIEWL DDTSCNVVWL DEMTATRALI NMSSLPAQDK IRSRDASEDK SAEKRKKDKQ EDSSDDDEAE EGEVEDENSS DVELDTLSQV EEESLLRNDL RPANKLAKGN (ATA-APrEST71648)