Anti-NALP1/NLRP1 (human) (AL176)

Anti-NALP1/NLRP1 (human) (AL176)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
AG-25B-0005-C100 100 µg -

3 - 9 business days

325.00€
 
Recognizes human NLRP1/NALP1. Does not cross-react with mouse NLRP1/NALP1. Liquid. Neat serum... more
Product information "Anti-NALP1/NLRP1 (human) (AL176)"
Recognizes human NLRP1/NALP1. Does not cross-react with mouse NLRP1/NALP1. Liquid. Neat serum containing 0.02% sodium azide. NALP1/NLRP1 is able to form cytoplasmic structures termed death effector filaments. It enhances and stimulates apoptosis through activation of different caspase cascades. It is involved in the activation of caspase-1 and caspase-5 as part of the NALP1 inflammasome complex which leads to processing and release of IL1B and IL18.Genetic variations in the NALP1/NLRP1 gene are associated with susceptibility to vitiligo-associated multiple autoimmune disease type 1, an autoimmune disorder characterized by the association of vitiligo with several autoimmune and autoinflammatory diseases including autoimmune thyroid disease, rheumatoid arthritis and systemic lupus erythematosus.
Keywords: NACHT-, LRR- and PYD-containing protein 1, Caspase recruitment domain-containing protein 7, Death effector filament-forming ced-4-like apoptosis protein, Nucleotide-binding domain and caspase recruitment domain
Supplier: Adipogen
Supplier-Nr: AG25B-0005-C100

Properties

Application: WB
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide corresponding to aa 2-25 (A2GGAWGRLACYLEFLKKEELKEFQ25) at the N-terminal human NLRP1/NALP1.

Database Information

KEGG ID : K12798 | Search using KEGG ID
UniProt ID : Q9C000 | Search using UniProt ID

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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