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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Discount | Price |
---|---|---|---|---|---|---|---|---|
AG-25B-0005-C100 | 100 µg | - |
3 - 9 business days* |
10 %
|
374.00€
336.60€ |
Recognizes human NLRP1/NALP1. Does not cross-react with mouse NLRP1/NALP1. Liquid. Neat serum... more
Product information "Anti-NALP1/NLRP1 (human) (AL176)"
Recognizes human NLRP1/NALP1. Does not cross-react with mouse NLRP1/NALP1. Liquid. Neat serum containing 0.02% sodium azide. NALP1/NLRP1 is able to form cytoplasmic structures termed death effector filaments. It enhances and stimulates apoptosis through activation of different caspase cascades. It is involved in the activation of caspase-1 and caspase-5 as part of the NALP1 inflammasome complex which leads to processing and release of IL1B and IL18.Genetic variations in the NALP1/NLRP1 gene are associated with susceptibility to vitiligo-associated multiple autoimmune disease type 1, an autoimmune disorder characterized by the association of vitiligo with several autoimmune and autoinflammatory diseases including autoimmune thyroid disease, rheumatoid arthritis and systemic lupus erythematosus.
Keywords: | NACHT-, LRR- and PYD-containing protein 1, Caspase recruitment domain-containing protein 7, Death effector filament-forming ced-4-like apoptosis protein, Nucleotide-binding domain and caspase recruitment domain |
Supplier: | AdipoGen Life Sciences |
Supplier-Nr: | AG-25B-0005 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Synthetic peptide corresponding to aa 2-25 (A2GGAWGRLACYLEFLKKEELKEFQ25) at the N-terminal human NLRP1/NALP1. |
Database Information
KEGG ID : | K12798 | Matching products |
UniProt ID : | Q9C000 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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