Anti-MYPT1 (Myosin phosphatase-targeting subunit 1, Myosin phosphatase target subunit 1, MYPT1, Prot

Anti-MYPT1 (Myosin phosphatase-targeting subunit 1, Myosin phosphatase target subunit 1, MYPT1, Prot
Item number Size Datasheet Manual SDS Delivery time Quantity Price
M9925-01C.100 100 µl - -

3 - 19 business days*

505.00€
 
Protein phosphatase 1 (PP1) is a ubiquitous eukaryotic protein serine/threonine phosphatase... more
Product information "Anti-MYPT1 (Myosin phosphatase-targeting subunit 1, Myosin phosphatase target subunit 1, MYPT1, Prot"
Protein phosphatase 1 (PP1) is a ubiquitous eukaryotic protein serine/threonine phosphatase involved in the regulation of various cell functions. Substrate specificity is determined by the binding of a regulatory subunit to the PP1 catalytic subunit (PP1c). It is estimated that over fifty different regulatory subunits exist. The myosin phosphatase holoenzyme is composed of three subunits: the PP1 catalytic subunit (PP1c), a targeting/regu- latory subunit (MYPT/myosin-binding subunit of myosin phosphatase) and a 20 kD subunit of unknown function (M20). MYPT binding to PP1c delta alters the conforma- tion of the catalytic cleft and increases enzyme activity and specificity. Two MYPT isoforms that are 61% identical have been described. MYPT1 is widely expressed while MYPT2 expression appears to be exclusive to heart and brain. Related family members also include MBS85, MYPT3 and TIMAP. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: United States Biological
Supplier-Nr: M9925-01C

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Hamster, Human, Monkey, Mouse, Rat
Immunogen: Synthetic peptide (KLH-coupled) correspondent to amino-terminal residues of human MYPT1.
Format: Affinity Purified

Database Information

Handling & Safety

Storage: -20°C (-20°C Glycerol)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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