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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES14598.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES14598.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness... more
Product information "Anti-MYOF"
Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined. [provided by RefSeq, Dec 2008], Protein function: Calcium/phospholipid-binding protein that plays a role in the plasmalemma repair mechanism of endothelial cells that permits rapid resealing of membranes disrupted by mechanical stress. Involved in endocytic recycling. Implicated in VEGF signal transduction by regulating the levels of the receptor KDR. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000. Cellular localization: Cell membrane, Single-pass type II membrane protein. Nucleus membrane, Single-pass type II membrane protein. Cytoplasmic vesicle membrane, Single-pass type II membrane protein. Concentrated at the membrane sites of both myoblast-myoblast and myoblast-myotube fusions. Detected at the plasmalemma in endothelial cells lining intact blood vessels (By similarity). Found at nuclear and plasma membranes. Enriched in undifferentiated myoblasts near the plasma membrane in puncate structures. .
Keywords: | Anti-MYOF, Anti-FER1L3, Anti-Myoferlin, Anti-Fer-1-like protein 3, MYOF rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES14598 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | Synthesized peptide derived from human MYOF AA range: 868-918 |
Format: | Purified |
Database Information
KEGG ID : | K22125 | Matching products |
UniProt ID : | Q9NZM1 | Matching products |
Gene ID | GeneID 26509 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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