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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
This gene encodes a protein which contains a C-terminal domain able to interact with the... more
Product information "Anti-MTUS1"
This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. Protein function: Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth. [The UniProt Consortium]
Keywords: | Anti-ATBP, Anti-MTUS1, Anti-AT2 receptor-binding protein, Anti-Mitochondrial tumor suppressor 1, Anti-Microtubule-associated tumor suppressor 1, Anti-Angiotensin-II type 2 receptor-interacting protein, MTUS1 Polyclonal Antibody |
Supplier: | Elabscience |
Supplier-Nr: | E-AB-66072 |
Properties
Application: | IF |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Recombinant fusion protein of human MTUS1 (NP_065800.1). |
Database Information
UniProt ID : | Q9ULD2 | Matching products |
Gene ID | GeneID 57509 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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