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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
M4692-74C.100 | 100 µl | - | - |
3 - 19 business days* |
682.00€
|
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Msh homeobox 1 (Msx1) is a Muscle Seg-ment Homeobox (Msh) gene family member that acts as a... more
Product information "Anti-Msx1 (Msh Homeobox 1, Msh Homeobox Homolog 1, Msx-1, Homeobox Protein MSX-1, Homeobox Protein M"
Msh homeobox 1 (Msx1) is a Muscle Seg-ment Homeobox (Msh) gene family member that acts as a transcriptional repressor during embryonic development, playing an important role in limb pattern formation, cranio-facial development, and tooth development (1-3). Msx1 is , expressed in the mesenchyme of the developing nail bed (2) and in fetal hair follicles, epidermis and fibroblasts, reduced expression is seen in adult epithelial-derived tissues (4). , Msx1 acts in concert with the Wnt1 network to establish the midbrain dopaminergic progenator domain, a region that gives rise to neurons that are critical for normal brain function and are the cells affected in Parkinson disease (5). Mutation in the corresponding Msx1 gene correlates with , abnormal tooth development in patients diagnosed with Wolf-Hirschhorn syndrome (6). Other genetic changes in the Msx1 gene result in Witkop Syndrome ("tooth and nail syndrome") and cases of abnormal tooth development as-sociated with non-syndromic orofacial clefting (2,7). Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1000. Incubate membrane with diluted antibody in 5% nonfat dry milk, 1X TBS, 0.1% Tween-20 at 4°C with gentle shaking, overnight. , Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-Homeobox protein Hox-7, Anti-Homeobox protein MSX-1, Anti-Msh homeobox 1-like protein |
Supplier: | United States Biological |
Supplier-Nr: | M4692-74C |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Synthetic peptide corresponding to amino acid sequence surrounding Gly116 of human Msx1 protein (KLH-coupled). |
Format: | Affinity Purified |
Database Information
KEGG ID : | K09341 | Matching products |
UniProt ID : | P28360 | Matching products |
Gene ID | GeneID 4487 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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