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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
G-HDBS0103.100 | 100 µg | - | - |
9 - 20 business days* |
399.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Receptor tyrosine kinase that transduces signals from the extracellular matrix... more
Product information "Anti-MST1R (Narnatumab Biosimilar Antibody)"
Protein function: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1 or the adapter GAB1. Recruitment of these downstream effectors by RON leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. RON signaling activates the wound healing response by promoting epithelial cell migration, proliferation as well as survival at the wound site. Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages. Alternatively, RON can also promote signals such as cell migration and proliferation in response to growth factors other than MST1 ligand. [The UniProt Consortium]
Keywords: | Anti-PTK8, Anti-MST1R, EC=2.7.10.1 |
Supplier: | Assay Genie |
Supplier-Nr: | HDBS0103 |
Properties
Application: | ELISA |
Antibody Type: | Monoclonal |
Conjugate: | No |
Host: | Human |
Species reactivity: | human |
Format: | Lyophilized |
Database Information
KEGG ID : | K05100 | Matching products |
UniProt ID : | Q04912 | Matching products |
Gene ID | GeneID 4486 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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