Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay32300-100 | 100 µl | - |
6 - 10 business days* |
480.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
MutS homolog 2 (MSH2) is a DNA repair protein. It heterodimerizes with MSH6 or MSH3 to form the... more
Product information "Anti-MSH2 Rabbit Monoclonal Antibody (Clone RM375)"
MutS homolog 2 (MSH2) is a DNA repair protein. It heterodimerizes with MSH6 or MSH3 to form the MutSalpha and MutSbeta DNA mismatch recognition complexes, respectively, which are divided into five domains: a mismatch-binding domain, connector domain, alpha-helical lever domain, clamp domain, and an ABC-ATPase domain. It is ubiquitously expressed and localized to the nucleus. MSH2, when complexed with MSH6 or MSH3, recognizes DNA polymerase errors in replicated DNA to activate MutL and initiate DNA repair. Missense mutations in MSH2 are associated with hereditary nonpolyposis colorectal cancer (HNPCC). Polymorphisms in MSH2 are associated with an increased risk of developing prostate cancer. Cayman's MSH2 Rabbit Monoclonal Antibody (Clone RM375) can be used for immunohistochemistry (IHC) and Western blot (WB) applications.Synonyms: DNA Mismatch Repair Protein MSH2, HNPCC1, MutS Homolog 2. Immunogen: Recombinant peptide within 500 amino acids of the N-terminus of human MSH2. Clone Designation: RM375. Formulation: (Request formulation change), 100 µl of protein A-affinity purified monoclonal antibody. Storage Buffer: PBS with 50% glycerol, 1% BSA, and 0.09% sodium azide. Host: Rabbit. Isotype: IgG. Applications: IHC, WB. Cross Reactivity: (+) MSH2.
Keywords: | DNA Mismatch Repair Protein MSH2, HNPCC1, MutS Homolog 2 |
Supplier: | Cayman Chemical |
Supplier-Nr: | 32300 |
Properties
Application: | IHC, WB |
Antibody Type: | Monoclonal |
Clone: | RM375 |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Recombinant peptide within 500 amino acids of the N-terminus of human MSH2 |
Format: | Purified |
Database Information
KEGG ID : | K08735 | Matching products |
UniProt ID : | P43246 | Matching products |
Gene ID | GeneID 4436 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed